RAP1A Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Induces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Together with ITGB1BP1, regulates KRIT1 localization to microtubules and membranes. Plays a role in nerve growth factor (NGF) -induced neurite outgrowth. Plays a role in the regulation of embryonic blood vessel formation. Involved in the establishment of basal endothelial barrier function. May be involved in the regulation of the vascular endothelial growth factor receptor KDR expression at endothelial cell-cell junctions.
Synonyms
RAP1; C21KG; G-22K; KREV1; KREV-1; SMGP21; Ras-related protein Rap-1A; GTP-binding protein smg p21A; Ras-related protein Krev-1; RAP1A
Gene ID
5906
Swiss Prot
P62834
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Immunogen
101-184/184
Target
RAP1A
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human RAP1A
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
5906
Predicted Cross Reactivity
Rat, Cow, Horse, Chicken
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS9905126 Inquire
Goose Differentially Expressed in FDCP 6 Homolog (DEF6) ELISA Kit
Ask
View Details