PIEZO1 Polyclonal Antibody, AbBy Fluor™ 405 Conjugated

Product Specifications

Background

Piezos are large transmembrane proteins conserved among various species, all having between 24 and 36 predicted transmembrane domains. 'Piezo' comes from the Greek 'piesi, ' meaning 'pressure.' The FAM38A gene encodes PIEZO1, a protein that induces mechanically activated (MA) currents in various cell types. PIEZO2 Component of a mechanosensitive channel required for rapidly adapting mechanically activated (MA) currents. Required for Merkel-cell mechanotransduction. Plays a major role in light-touch mechanosensation

Synonyms

Piezo-type mechanosensitive ion channel component 1; Piezo-type mechanosensitive ion channel component 2; PIEZO1; PIEZO2; Mib; C18orf30; C18orf58; FAM38B; FAM38A; KIAA0233

Gene ID

9780

Swiss Prot

Q92508

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse

Immunogen

2451-2521/2521

Target

PIEZO1

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 405

Source

KLH conjugated synthetic peptide derived from human PIEZO1

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

401nm/421nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

9780

Predicted Cross Reactivity

Rat, Dog, Cow, Sheep

Available Sizes

Curated Selection

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