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DSCR3 Polyclonal Antibody, AbBy Fluor™ 594 Conjugated

Product Specifications

Background

The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq, Jul 2008]

Synonyms

DCRA; DSCRA; Down syndrome critical region protein 3; Down syndrome critical region protein A; DSCR3

Gene ID

10311

Swiss Prot

O14972

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Rat

Immunogen

1-100/297

Target

DSCR3

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 594

Source

KLH conjugated synthetic peptide derived from human DSCR3

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

590nm/617nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

10311

Predicted Cross Reactivity

Human, Mouse

Curated Selection

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