DNASE1L2 Polyclonal Antibody, AbBy Fluor™ 555 Conjugated
Product Specifications
Background
DNASE1L2 is a 299 amino acid secreted protein that is expressed in brain tissue and shares sequence similarity with DNase I, suggesting a possibly role in DNA hydrolysis. The gene encoding DNASE1L2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
Synonyms
Deoxyribonuclease I-like 2; Deoxyribonuclease-1-like 2; DNase I homolog protein DHP1; DNase I-like 2; Dnase1l2; DNSL2_HUMAN.
Gene ID
1775
Swiss Prot
Q92874
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Rat
Immunogen
201-299/299
Target
DNASE1L2
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 555
Source
KLH conjugated synthetic peptide derived from human DNASE1L2
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
553nm/568nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1775
Predicted Cross Reactivity
Human, Mouse, Cow, Sheep, Pig, Horse, Rabbit
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