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DNASE1L2 Polyclonal Antibody, APC-Cy5.5 Conjugated

Product Specifications

Background

DNASE1L2 is a 299 amino acid secreted protein that is expressed in brain tissue and shares sequence similarity with DNase I, suggesting a possibly role in DNA hydrolysis. The gene encoding DNASE1L2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Synonyms

Deoxyribonuclease I-like 2; Deoxyribonuclease-1-like 2; DNase I homolog protein DHP1; DNase I-like 2; Dnase1l2; DNSL2_HUMAN.

Gene ID

1775

Swiss Prot

Q92874

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Rat

Immunogen

201-299/299

Target

DNASE1L2

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy5.5

Source

KLH conjugated synthetic peptide derived from human DNASE1L2

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/694nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.biossantibodies.com/datasheets/bs-14395R-APC-Cy5.5

Gene ID URL

1775

Predicted Cross Reactivity

Human, Mouse, Cow, Sheep, Pig, Horse, Rabbit

Curated Selection

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