MRP5 Polyclonal Antibody, FITC Conjugated

MRP5 (190-200 kDa) is closely related to MRP4, both lacking the first five membrane spanning regions. MRP5 is a GS-X multi specific organic anion pump (nucleotide analogs) . MRP5 may transport DNP-GS and may be inhibited by certain inhibitors of organic anion transport (sulfinpyrazone) . MRP5 may also transport organic anions with the anionic moiety of phosphate/phosphonate group, a function which provides the ability to resist against anti cancer drugs 6-MP and thioguanine as well as the anti-HIV drug PMEA.

Multidrug Resistanec-Associated Protein 5; ABC 33; ABC33; ABCC 5; ABCC5; ATP binding cassette sub family C CFTR/MRP member 5; ATP binding cassette sub family C member 5; Canalicular multispecic organic anion transporter C; DKFZp686C1782; EST277145; MOAT C; MOATC; MRP 5; Multi specic organic anion tranporter C; pABC 11; pABC11; SMRP; MRP5_HUMAN.