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MRP5 Polyclonal Antibody

Product Specifications

Background

MRP5 (190-200 kDa) is closely related to MRP4, both lacking the first five membrane spanning regions. MRP5 is a GS-X multi specific organic anion pump (nucleotide analogs) . MRP5 may transport DNP-GS and may be inhibited by certain inhibitors of organic anion transport (sulfinpyrazone) . MRP5 may also transport organic anions with the anionic moiety of phosphate/phosphonate group, a function which provides the ability to resist against anti cancer drugs 6-MP and thioguanine as well as the anti-HIV drug PMEA.

Synonyms

Multidrug Resistanec-Associated Protein 5; ABC 33; ABC33; ABCC 5; ABCC5; ATP binding cassette sub family C CFTR/MRP member 5; ATP binding cassette sub family C member 5; Canalicular multispecic organic anion transporter C; DKFZp686C1782; EST277145; MOAT C; MOATC; MRP 5; Multi specic organic anion tranporter C; pABC 11; pABC11; SMRP; MRP5_HUMAN.

Gene ID

10057

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Rat

Immunogen

61-180/1436

Target

MRP5

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human MRP5

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

10057

Predicted Cross Reactivity

Human, Mouse

Curated Selection

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