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Histone H1t Polyclonal Antibody, Biotin Conjugated

Product Specifications

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Synonyms

HIST1H1T; H1FT; H1T; H1T_HUMAN; Histone H1t; Testicular H1 histone.

Gene ID

3010

Swiss Prot

P22492

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Mouse, Rat

Immunogen

51-207/207

Target

Histone H1t

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human Testicular H1 histone

Applications

WB, ELISA

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

3010

Predicted Cross Reactivity

Human, Dog, Cow, Pig, Horse, Rabbit

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