Phospho-Cyclin C (Ser275) Polyclonal Antibody, PE Conjugated

Product Specifications

Background

The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Synonyms

Cyclin C (phospho S275) ; p-Cyclin C (phospho S275) ; CCNC; CCNC_HUMAN; CycC; Cyclin C; Cyclin-C; CyclinC; hSRB11; OTTHUMP00000016897; SRB11 homolog

Gene ID

892

Swiss Prot

P24863

Modification Site

Ser275

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Phospho-Cyclin C (Ser275)

Clonality

Polyclonal

Isotype

IgG

Conjugation

Source

KLH conjugated Synthesised phosphopeptide derived from human Cyclin C around the phosphorylation site of Ser275

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

892

Predicted Cross Reactivity

Dog, Cow, Sheep, Horse, Chicken

Curated Selection

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