Phospho-Cyclin C (Ser275) Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
Cyclin C (phospho S275) ; p-Cyclin C (phospho S275) ; CCNC; CCNC_HUMAN; CycC; Cyclin C; Cyclin-C; CyclinC; hSRB11; OTTHUMP00000016897; SRB11 homolog
Gene ID
892
Swiss Prot
P24863
Modification Site
Ser275
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Phospho-Cyclin C (Ser275)
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated Synthesised phosphopeptide derived from human Cyclin C around the phosphorylation site of Ser275
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
892
Predicted Cross Reactivity
Dog, Cow, Sheep, Horse, Chicken
Curated Selection
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