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CTDSP2 Polyclonal Antibody, PE-Cy5.5 Conjugated

Product Specifications

Background

Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.

Synonyms

OS4; PSR2; SCP2; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2; Nuclear LIM interactor-interacting factor 2; NLI-interacting factor 2; Protein OS-4; Small C-terminal domain phosphatase 2; Small CTD phosphatase 2; CTDSP2; NIF2

Gene ID

10106

Swiss Prot

O14595

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

25-150/271

Target

CTDSP2

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE-Cy5.5

Source

KLH conjugated synthetic peptide derived from human CTDSP2

Applications

FCM

Purification

Purified by Protein A.

Excitation Emission

488nm/694nm

Concentration

1µg/µl

Dilution

FCM (1:20-100)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

10106

Predicted Cross Reactivity

Mouse, Cow, Sheep, Pig, Horse, Rabbit

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