Crry Polyclonal Antibody, PE Conjugated
Product Specifications
Background
Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion.
Synonyms
Mcp; Crry; mCRY; Complement component receptor 1-like protein; Complement regulatory protein Crry; Protein p65; Cr1l; Cry
Gene ID
12946
Swiss Prot
Q64735
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
51-150/559
Target
Crry
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human Crry
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
12946
Predicted Cross Reactivity
Rat
Curated Selection
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