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Crry Polyclonal Antibody, AbBy Fluor™ 350 Conjugated

Product Specifications

Background

Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion.

Synonyms

Mcp; Crry; mCRY; Complement component receptor 1-like protein; Complement regulatory protein Crry; Protein p65; Cr1l; Cry

Gene ID

12946

Swiss Prot

Q64735

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

51-150/559

Target

Crry

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 350

Source

KLH conjugated synthetic peptide derived from human Crry

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

346nm/442nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

12946

Predicted Cross Reactivity

Rat

Curated Selection

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