COPG2 Polyclonal Antibody, PE Conjugated
Product Specifications
Background
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
Synonyms
2 COP; Coat protein nonclathrin gamma 2 cop; Coatomer protein complex subunit gamma 2; Coatomer subunit gamma 2; Coatomer subunit gamma-2; COPG 2; Copg2; COPG2_HUMAN; DKFZp761N09121; FLJ11781; Gamma 2 coat protein; Gamma 2 COP; Gamma-2-coat protein; Gamma-2-COP; Coatomer subunit gamma-1; COPG1; Gamma-1-coat protein; Gamma-1-COP; COPG
Gene ID
22820; 26958
Swiss Prot
Q9Y678; Q9UBF2
Cellular Locus
Cytoplasm
Host
Rabbit
Immunogen
1-100/871
Target
COPG2
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human COPG2
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
22820; 26958
Predicted Cross Reactivity
Human, Mouse, Rat, Cow
Curated Selection
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