Cdc6 Polyclonal Antibody
Product Specifications
Background
Cell cycle events are regulated by the sequential activation and deactivation of cyclin depended kinase (Cdks) and by the proteolysis of cyclins. The cell division cycle (Cdc) genes are required at various points in the cell cycle. Cdc6 is the human homolog of Saccharomyces cerevisiae Cdc6, which is involved in the initiation of DNA replication. Cdc6 is essential for assembling the pre-replicative complex that forms at origins of DNA replication in the G1 phase of the cell cycle in budding yeast (S. cerevisiae) . Cdc6 is also involved in checkpoint controls that ensure that DNA replication is completed before initiation of mitosis.
Synonyms
Cell Division Cycle protein 6; Cdc 18L; Cdc 6; CDC18 cell division cycle 18, S.pombe, homolog like; CDC18 S.pombe; CDC18 like; CDC18S.pombe; Cdc18L; CDC6 related protein; Cdc6p; Cell cycle controller; Cell division control protein 6; Cell division control protein 6 homolog; Cell division cycle 18; Cell division cycle 18 homolog; Cell division cycle 6 homolog; Cell division cycle 6 protein; HsCDC 18; HsCDC 6; HsCDC18; HsCDC6; p62; p62cdc 6; p62cdc6.
Gene ID
990
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Cdc6
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human Cdc6
Applications
WB, IHC-P, IHC-F, IF, Flow-Cyt, ICC/IF
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (WB=1:500-2000), IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:100-500), IF (IF=1:100-500), Flow-Cyt (Flow-Cyt=1ug/Test), ICC/IF (ICC/IF=1:100)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
990
Curated Selection
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