APG4B Polyclonal Antibody, APC Conjugated

Product Specifications

Background

Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Synonyms

APG4B; AUTL1; Cysteine protease ATG4B; AUT-like 1 cysteine endopeptidase; Autophagin-1; Autophagy-related cysteine endopeptidase 1; Autophagy-related protein 4 homolog B; hAPG4B; ATG4B; KIAA0943

Gene ID

23192

Swiss Prot

Q9Y4P1

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

85-200/392

Target

APG4B

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human ATG4B

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

23192

Predicted Cross Reactivity

Dog, Cow

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP3-16625-20ul 20 µL

Rabbit Monoclonal CEACAM6/CD66c Antibody (4Z3V7)

Ask

View Details

HY-P85739 1 Each

MEK2 Antibody (YA5431, Mouse)

Ask

View Details

NBP2-52408PCP 0.1 mL

Mouse Monoclonal PD-L2/B7-DC/PDCD1LG2 Antibody (Z64P2D3*H4) [PerCP]

Ask

View Details

E51A03670 100 µL

HEXIM1 Antibody

Ask

View Details