1,6,7-Trihydroxyxanthone
Product Specifications
UNSPSC Description
1,6,7-Trihydroxyxanthone is a potent anticancer agent. 1,6,7-Trihydroxyxanthone inhibits cell proliferation and induces cell Apoptosis. 1,6,7-Trihydroxyxanthone decreases Bmi-1 expressio and increases the protein levels expression of P14, P16[1].
Target Antigen
Apoptosis; BMI1
Type
Natural Products
Related Pathways
Apoptosis;Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/1-6-7-trihydroxyxanthone.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(OC3=C1C=C(O)C(O)=C3)C=CC=C2O
Molecular Weight
244.20
References & Citations
[1]Fu WM, et al. MiR-218-targeting-Bmi-1 mediates the suppressive effect of 1,6,7-trihydroxyxanthone on liver cancer cells. Apoptosis. 2015 Jan;20(1):75-82.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N0992/1-6-7-Trihydroxyxanthone-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N0992/
Clinical Information
No Development Reported
CAS Number
25577-04-2
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