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Claudin 16 Polyclonal Antibody, AbBy Fluor™ 750 Conjugated

Product Specifications

Background

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in paracellular magnesium reabsorption. Required for a selective paracellular conductance. May form, alone or in partnership with other constituents, an intercellular pore permitting paracellular passage of magnesium and calcium ions down their electrochemical gradients. Alternatively, it could be a sensor of magnesium concentration that could alter paracellular permeability mediated by other factors.

Synonyms

HOMG3; PCLN1; Claudin-16; Paracellin-1; PCLN-1; CLDN16

Gene ID

10686

Swiss Prot

Q9Y5I7

Cellular Locus

Cell membrane

Host

Rabbit

Immunogen

95-150/305

Target

Claudin 16

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 750

Source

KLH conjugated synthetic peptide derived from human Claudin 16

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

749nm/775nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

10686

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Cow, Sheep, Chicken, Rabbit

Available Sizes

Curated Selection

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