Claudin 16 Polyclonal Antibody, APC Conjugated
Product Specifications
Background
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in paracellular magnesium reabsorption. Required for a selective paracellular conductance. May form, alone or in partnership with other constituents, an intercellular pore permitting paracellular passage of magnesium and calcium ions down their electrochemical gradients. Alternatively, it could be a sensor of magnesium concentration that could alter paracellular permeability mediated by other factors.
Synonyms
HOMG3; PCLN1; Claudin-16; Paracellin-1; PCLN-1; CLDN16
Gene ID
10686
Swiss Prot
Q9Y5I7
Cellular Locus
Cell membrane
Host
Rabbit
Immunogen
95-150/305
Target
Claudin 16
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human Claudin 16
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
10686
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Sheep, Chicken, Rabbit
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