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SPANXB1 Polyclonal Antibody

Product Specifications

Background

A variety of morphological and molecular changes are required for mature spermatozoa formation. These steps are temporally guided by the transcription and translation of several testis-specific genes. SPANX (sperm protein associated with the nucleus, X-linked) family members are sperm- and testis-specific proteins containing between 97-103 amino acids, whose genes form a cluster on chromosome X. Sharing a high level of sequence similarity, SPANX-A, -B, -C, -D and -E localize to both cytoplasm and nucleus where they are associated with nuclear craters. SPANX-B (Sperm protein associated with the nucleus on the X chromosome B/F) is a 103 amino acid protein that is detected in round and elongating spermatids.

Synonyms

Cancer/testis antigen 11.2; Cancer/testis antigen family 11, member 2; CT11.2; hCG2036708; Nuclear associated protein SPAN Xb; Nuclear-associated protein SPAN-Xb; Nuclear-associated protein SPAN-Xf; SPAN Xb protein; SPAN Xf; SPANX; SPANX B; SPANX C; SPANX F; SPANX family member B/F; SPANX family, member B1; SPANX family, member B2; SPANX family, member F1; SPANX-B; SPANX-F; SPANXB; SPANXB2; SPANXF; SPANXF1; Sperm protein associated with the nucleus on the X chromosome B/F; Sperm protein associated with the nucleus, X chromosome, family; Sperm protein associated with the nucleus, X chromosome, family member B1; Sperm protein associated with the nucleus, X chromosome, family member B2; SPNXB_HUMAN.

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Immunogen

1-80/103

Target

SPANXB1

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human SPANXB1

Applications

ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Predicted Cross Reactivity

Human

Curated Selection

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