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ZBTB5 Polyclonal Antibody, APC Conjugated

Product Specifications

Background

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 5 (ZBTB5) is a 677 amino acid member of the Kr_ppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB5 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB5 functions as a transcription regulator.

Synonyms

5930421I10; 9430083K24Rik; AI646847; Expressed in brain and neural tube; KIAA0354; mKIAA0354; OTTMUSP00000007812; OTTMUSP00000007813; OTTMUSP00000007814; RP11-397D12.5; RP23-218A4.2; Transcription factor ZNF POZ; Zbtb5; ZBTB5_HUMAN; Zinc finger and BTB domain containing protein 5; Zinc finger and BTB domain-containing protein 5.

Gene ID

9925

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Immunogen

581-677/677

Target

ZBTB5

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human ZBTB5

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

9925

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Sheep, Horse, Chicken, Rabbit

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