ZBTB46 Polyclonal Antibody, RBITC Conjugated
Product Specifications
Background
BTBD4 is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.
Synonyms
BTB/POZ domain containing protein 4; BTBD4; RINZF; Zinc finger and BTB domain containing 46; Zinc finger and BTB domain containing protein 46; Zinc finger protein 340; ZNF340; ZBT46_HUMAN.
Gene ID
140685
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
401-500/589
Target
ZBTB46
Clonality
Polyclonal
Isotype
IgG
Conjugation
RBITC
Source
KLH conjugated synthetic peptide derived from human ZBTB46/BTBD4
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
570nm/595nm
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
140685
Predicted Cross Reactivity
Human, Rat, Sheep, Horse, Chicken
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
124552-HRP 100 µL
CD178 (Apoptosis Antigen Ligand, APT1LG1, APTL, CD95 Ligand, CD95L, CD95-L, FAS Antigen Ligand, Fas Ligand, FASL, FASLG, Tumor Necrosis Factor Ligand Superfamily Member 6, TNFSF6) (HRP)
Ask
View Details 