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ZBTB46 Polyclonal Antibody, AbBy Fluor™ 750 Conjugated

Product Specifications

Background

BTBD4 is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.

Synonyms

BTB/POZ domain containing protein 4; BTBD4; RINZF; Zinc finger and BTB domain containing 46; Zinc finger and BTB domain containing protein 46; Zinc finger protein 340; ZNF340; ZBT46_HUMAN.

Gene ID

140685

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

401-500/589

Target

ZBTB46

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 750

Source

KLH conjugated synthetic peptide derived from human ZBTB46/BTBD4

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

749nm/775nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

140685

Predicted Cross Reactivity

Human, Rat, Sheep, Horse, Chicken

Curated Selection

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