GPR26 Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation) . GPR signaling is an ancient evolutionarily mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. GPRs have seven membrane-spanning domains and the extracellular domains are often glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. GPR26 (G-protein coupled receptor 26) is a 337 amino acid protein that is primarily expressed in regions of the brain. GPR26 is characterized as an orphan? G protein-coupled receptor, which is a receptor that binds an unidentified natural ligand. Due to evidence of GPR26 being downregulated in glioblastomas, it has been suggested that GPR26 may be a suppressor of early glioma development.
Synonyms
AXOR49; DKFZp761H2121; FLJ33774; G protein-coupled receptor 26; G protein-coupled receptor 26; G protein-coupled receptor GPR26; MGC138216; GPR26_HUMAN; GPCR GPR26.
Gene ID
2849
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Immunogen
101-200/337
Target
GPR26
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human G protein-coupled receptor 26
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
2849
Predicted Cross Reactivity
Mouse, Rat, Dog, Cow, Sheep, Pig, Horse
Curated Selection
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