GPR 151 Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
GPCR2037 is a G protein-coupled receptor that undergoes weak activation by Galanin and is most abundant in the central nervous system (CNS), where it appears to be critical for development. During embryonal development the expression of GPCR2037 is widespread in the nervous system (dorsal thalamus, striatum, locus coeruleus and hindbrain nuclei) . GPCR2037 in the CNS of 7- and 15-day-old mouse embryos can localize to the habenular complex. Low levels of GPCR2037 are detectable in testis, liver, kidney and stomach. In addition to GPCR2037, Galanin mediates its effects through receptor subtypes GALR1, 2 and 3. Galanin ligand exerts anxiolytic actions via GALR receptors under conditions of high stress. Galanin coexists with norepinephrine and serotonin in neural systems that mediate emotion.
Synonyms
G protein coupled receptor 151; G protein coupled receptor PGR7; G-protein coupled receptor PGR7; Galanin receptor 4; Galanin receptor like; GALR4; GALRL; GP151_HUMAN; GPCR; GPCR-2037; GPCR2037; GPR151; PGR7; Probable G protein coupled receptor 151; Probable G-protein coupled receptor 151; Putative G protein coupled receptor; GPCR GPR151.
Gene ID
134391
Swiss Prot
Q8TDV0
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
11-110/419
Target
GPR 151
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human GPR 151
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
134391
Predicted Cross Reactivity
Human, Cow, Sheep, Pig, Horse
Curated Selection
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