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Golgin subfamily A member 4 Polyclonal Antibody, PE Conjugated

Product Specifications

Background

Golgin 245 is also known as p230, GCP2, GOLG or golgi autoantigen and is a 2,230 amino acid protein that is expressed as three isoforms. Golgin 245 is localized to the cytoplasm in cells and is a member of the golgin family, all of which are peripheral membrane proteins associated with the Golgi complex. Golgin 245 has a carboxyl-terminal GRIP domain, which attaches to the trans-Golgi network (TGN) and TGN-derived vesicles. It is thought that the interaction that takes place between golgin 245 and MACF1, which cross-links microtubules to the Actin cytoskeleton, allows proteins to be transported from the TGN to the cell periphery. against golgin 245 are associated with two chronic disorders known as Sjren's syndrome and Hepatitis B.

Synonyms

256 kDa golgin; 72.1 protein; GCP2; GOGA4_HUMAN; GOLG; GOLGA4; golgi autoantigen, golgin subfamily a, 4; Golgin subfamily A member 4; golgin-240; Golgin-245; MU-RMS-40.18; OTTHUMP00000161363; OTTHUMP00000208897; OTTHUMP00000209805; p230; Protein 72.1; Trans-Golgi p230.

Gene ID

2803

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

2061-2160/2230

Target

Golgin subfamily A member 4

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE

Source

KLH conjugated synthetic peptide derived from human Golgin subfamily A member 4/Golgin 245

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2803

Predicted Cross Reactivity

Human, Rat, Cow, Pig, Horse, Rabbit

Curated Selection

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