Phospho-GluR1 (Thr840) Polyclonal Antibody, Cy3 Conjugated

Product Specifications

Background

Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Synonyms

Glutamate receptor 1; GluR-1; AMPA-selective glutamate receptor 1; GluR-A; GluR-K1; Glutamate receptor ionotropic, AMPA 1; GluA1; GRIA1; GLUH1; GLUR1

Gene ID

2890

Modification Site

Thr856

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Rat

Target

Phospho-GluR1 (Thr840)

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy3

Source

KLH conjugated synthetic phosphopeptide derived from human Glutamate Receptor 1 around the phosphorylation site of Thr856

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2890

Predicted Cross Reactivity

Mouse, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP2-90538C 0.1 mL

Rabbit Monoclonal PLA2G1B Antibody (004) [DyLight 650]

Ask

View Details

MBS5316451-01 0.1 mg

RVG Protein, Partial

Ask

View Details

MBS5316451-02 5x 0.1 mg

RVG Protein, Partial

Ask

View Details

A58776-50UG 50 µg

DCUN1D2 Antibody, HRP conjugated

Ask

View Details

A58472-100UG 100 µg

TTC33 Antibody

Ask

View Details

MBS7204134-01 48 Well

Canine Ankyrin repeat domain-containing protein 30A (ANKRD30A) ELISA Kit

Ask

View Details