GCM2 Polyclonal Antibody, APC-Cy7 Conjugated

Product Specifications

Background

Glial cells missing homolog 2 (GCM2), also known as Chorion-specific transcription factor GCMb, is a 506 amino acid nuclear protein. GCM2 is a transcription factor that acts as an essential regulator of parathyroid development. GCM2 is also thought to mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. GCM2 contains one N-terminal GCM domain, which has DNA binding activity. Mutations of the gene that encodes GCM2 are associated with hypoparathyroidism, an autosomal recessive condition characterized by hypocalcemia and hyperphosphatemia.

Synonyms

Chorion-specic transcription factor GCMb; GCM mot protein 2; GCMb; Glial cells missing homolog 2; glial cells missing homolog b; GCM2_HUMAN.

Gene ID

9247

Swiss Prot

O75603

Cellular Locus

Nucleus

Host

Rabbit

Immunogen

61-160/506

Target

GCM2

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy7

Source

KLH conjugated synthetic peptide derived from human GCM2

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/780nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

9247

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Pig, Horse, Rabbit

Curated Selection

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