FUT6 Polyclonal Antibody, APC Conjugated
Product Specifications
Background
Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which is an essential interface for biological recognition processes. Fucosyltransferases catalyze the covalent association of fucose to different positional linkages in sugar acceptor molecules. The carbohydrate moieties generated and covalently attached to cell surfaces are necessary to ensure a surface contour that satisfies physiological roles, which are reliant on adhesion molecules such as Selectins (1-3) . Hematopoietic lineages rely on Fucosyltransferases to confer a surface carbohydrate phenotype, which mediates proper cell adhesion molecule recruitment and cell trafficking (4-6) .
Synonyms
Alpha 1,3 fucosyltransferase; EC=2.4.1.65; FCT3A; Fuc TVI; Fucosyltransferase 6; Fucosyltransferase VI; FucT VI; Galactoside 3 L fucosyltransferase; FUT6_HUMAN.
Gene ID
2528
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Immunogen
101-200/359
Target
FUT6
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human FUT6/FucT-VI
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
2528
Predicted Cross Reactivity
Human
Curated Selection
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