FPGT Polyclonal Antibody, AbBy Fluor™ 405 Conjugated
Product Specifications
Background
Guanylyltransferase enzymes transfer one molecule of GTP to another molecule and also function in the transfer of guanosine nucleotides to sugar molecules. The carbohydrate moieties that are generated are covalently attached to cell surfaces and are necessary to ensure a surface contour that satisfies a variety of physiological roles. L-fucose is an important sugar in complex carbohydrates that is frequently found on plant and mammalian N-linked glycans. FPGT (Fucose-1-phosphate guanylyltransferase), also known as GFPP (GDP-L-fucose pyrophosphorylase), is a 594 amino acid cytoplasmic protein that catalyzes the formation of GDP-L-fucose from L-fucose-1-phosphate and GTP. FPGT functions to reutilize the L-fucose that is produced uopn glycoprotein and glycolipid turnover.
Synonyms
FPGT; FPGT_HUMAN; Fucose 1 phosphate guanyltransferase; Fucose 1 phosphate guanylyltransferase; Fucose-1-phosphate guanylyltransferase; GDP beta L fucose pyrophosphorylase; GDP L fucose diphosphorylase; GDP L fucose pyrophosphorylase; GDP-L-fucose diphosphorylase; GDP-L-fucose pyrophosphorylase; GFPP.
Gene ID
8790
Cellular Locus
Cytoplasm
Host
Rabbit
Immunogen
251-350/594
Target
FPGT
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 405
Source
KLH conjugated synthetic peptide derived from human FPGT
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
401nm/421nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
8790
Predicted Cross Reactivity
Human, Mouse, Rat, Dog
Curated Selection
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