Phospho-FOXO4 (Thr451) Polyclonal Antibody, APC-Cy5.5 Conjugated

Product Specifications

Background

FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.

Synonyms

FOXO4 phospho T451; p-FOXO4 phospho T451; AFXSer197; Fork head domain transcription factor AFX1; AFX; AFX1; Afxh; ALL1-fused gene from X chromosome; Fork head domain transcription factor AFX1; Forkhead box O4; Forkhead box protein O4; FOXO 4; Mixed lineage leukemia, translocated to, 7; MLLT7; Myeloid lymphoid or mixed lineage leukemia translocated to 7; Myeloid/lymphoid or mixed lineage leukemia, translocated to, 7; Putative fork head domain transcription factor AFX1; FOXO4_HUMAN.

Gene ID

4303

Modification Site

Thr451

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Rat

Target

Phospho-FOXO4 (Thr451)

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy5.5

Source

KLH conjugated synthetic phosphopeptide derived from human FOXO4 around the phosphorylation site of Thr451

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/694nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4303

Predicted Cross Reactivity

Mouse, Dog, Pig, Rabbit

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MR218238L3V 200 µL

Seh1l (NM_028112) Mouse Tagged ORF Clone Lentiviral Particle

Ask

View Details

33R-8060 100 ug

PDHA2 Blocking Peptide

Ask

View Details

JOT-EK1974Mo 96 wells

Mouse CpG-binding protein,CXXC1 ELISA KIT

Ask

View Details

MBS7054669 Inquire

Recombinant Schizosaccharomyces pombe Dolichol-phosphate mannosyltransferase subunit 3 (dpm3), partial

Ask

View Details

FC15001R-10 1 PC

Iris Forceps

Ask

View Details

159967 250 mg

2,5-Dichloro-N-[2- (isopropylsulfonyl) phenyl]pyrimidin-4-amine

Ask

View Details