Phospho-FMRP (Ser500) Polyclonal Antibody, PerCP Conjugated

Product Specifications

Background

Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity) . RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly (G), binds moderately to poly (U) but shows very little binding to poly (A) or poly (C) .

Synonyms

POF; FMRP; POF1; FRAXA; Fragile X mental retardation protein 1; Protein FMR-1; FMR1

Gene ID

2332

Swiss Prot

Q06787

Modification Site

Ser500

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Phospho-FMRP (Ser500)

Clonality

Polyclonal

Isotype

IgG

Conjugation

PerCP

Source

KLH conjugated synthetic phosphopeptide derived from human FMRP around the phosphorylation site of Ser500

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

482nm/677nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2332

Predicted Cross Reactivity

Dog, Cow, Sheep, Pig, Chicken, Rabbit, Guinea Pig, Zebrafish

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP3-08691B 100 µL

Mouse Monoclonal Cytokeratin 16 Antibody (KRT16/1714) [Biotin]

Ask

View Details

bsm-33035M-PerCP 100 µL

PCNA Monoclonal Antibody, PerCP Conjugated

Ask

View Details

HY-P80667-01 10 µL

Fascin Antibody (Rabbit)

Ask

View Details

HY-P80667-02 50 μL

Fascin Antibody (Rabbit)

Ask

View Details

HY-P80667-03 100 µL

Fascin Antibody (Rabbit)

Ask

View Details

CSB-MP023451HU2-01 20 µg

Recombinant Human TGF-beta receptor type-1 (TGFBR1), partial

Ask

View Details