Phospho-Filamin A (Ser1083) Polyclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking.
Synonyms
Filamin A phospho S1084; p-Filamin A phospho S1084; ABP 280; ABP 280 like protein; ABP-280; ABP280A; ABPA antibody Actin binding like protein; Actin binding protein 280; Actin-binding protein 280; Alpha filamin; Alpha-filamin; APBX; cb967; Dilp2; Endothelial actin binding protein; Endothelial actin-binding protein; Filamin 1; Filamin A alpha actin binding protein 280; Filamin A; Filamin-1; Filamin-A; FLN; FLN-A; FLN1; FLNA; FLNA_HUMAN; FMD; MNS; NHBP; Non muscle filamin; Non-muscle filamin; OPD; OPD1; OPD2.
Gene ID
2316
Modification Site
Ser1084
Cellular Locus
Cytoplasm
Host
Rabbit
Target
Phospho-Filamin A (Ser1083)
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic phosphopeptide derived from human FLNA around the phosphorylation site of Ser1084
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
2316
Predicted Cross Reactivity
Human, Mouse, Rat, Cow, Sheep, Pig, Rabbit
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