Phospho-FANCD2 (Ser1404) Polyclonal Antibody, AbBy Fluor™ 594 Conjugated
Selected Variant
bs-13141R-BF594
Size: 100 µL
Product Specifications
Background
Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC) . The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation. DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.
Synonyms
FANCD2 phospho S1404; FANCD2 phospho Ser1404; p-FANCD2 phospho S1404; FA 4; FA D2; FA4; FAC D2; FACD 2; FACD; FACD2; FAD; FAD2; FANC D2; FANCD 2; FANCD; Protein FACD2; Type 4 Fanconi pancytopenia; FACD2_HUMAN; Fanconi anemia group D2 protein; Protein FACD2.
Gene ID
2177
Modification Site
Ser1404
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Target
Phospho-FANCD2 (Ser1404)
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 594
Source
KLH conjugated synthetic phosphopeptide derived from human FANCD2 around the phosphorylation site of Ser1404
Applications
FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
590nm/617nm
Concentration
1µg/µl
Dilution
FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
2177
Predicted Cross Reactivity
Cow, Sheep, Pig, Horse, Rabbit
Price
Sign In for Pricing
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
A01276-2-Cy3 100 µg/Vial
Anti-VEGF Receptor 3/FLT4 Antibody Picoband® (Cy3 Conjugate)
Sign In for Pricing
View Details 
BNC743280-100 1x 100 µL
Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) (TYRP1/3280), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
EK0459 96 Well With Removable Strips
Human MMP-2 ELISA Kit PicoKine®
Sign In for Pricing
View Details 
BNC882414-100 1x 100 µL
MDM2 (MDM2/2414), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
EK2372 96 Well With Removable Strips
Feline IL-8 ELISA Kit PicoKine®
Sign In for Pricing
View Details ![MERTK Recombinant Rabbit Monoclonal Antibody [SR29-07]](https://cdn.genprice.uk/products/992/68dd1c8a061270361ea81248/imageurl/et1602-21.webp)
ET1602-21 100 µL
MERTK Recombinant Rabbit Monoclonal Antibody [SR29-07]
Sign In for Pricing
View Details