FAM134B Polyclonal Antibody, PE-Cy7 Conjugated
Product Specifications
Background
Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes (PubMed:26040720) . Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins (PubMed:26040720) . Required for long-term survival of nociceptive and autonomic ganglion neurons (PubMed:19838196, PubMed:26040720) .
Synonyms
JK1; JK-1; Reticulophagy receptor FAM134B; FAM134B
Gene ID
54463
Swiss Prot
Q9H6L5
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
210-310/497
Target
FAM134B
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE-Cy7
Source
KLH conjugated synthetic peptide derived from human FAM134B
Applications
WB, FCM
Purification
Purified by Protein A.
Excitation Emission
488nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Specificity
There is a chance that this protein will cross-react with MSL2 based on a 73% non-sequential sequence similarity.
Gene ID URL
54463
Predicted Cross Reactivity
Cow, Rabbit
Curated Selection
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