EXOSC7 Polyclonal Antibody, APC Conjugated
Product Specifications
Background
The exosome is a multisubunit complex of 3? to 5? exoribonucleases. It is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich elements in their untranslated 3? region. EXOSC7 (exosome component 7), also known as p8, EAP1, RRP42 (Ribosomal RNA-processing protein 42), Rrp42p or hRrp42p, is a component of the exosome multienzyme ribonuclease complex. It belongs to the RNase PH family and localizes to the nucleolus. EXOSC7 is one of the six RNase-PH domain subunits of the exosome. Together, these six subunits form a PNPase-like ring. EXOSC7 is required for the processing of the 7S pre-RNA.
Synonyms
EAP1; EXOS7_HUMAN; Exosc7; Exosome complex component RRP42; Exosome complex exonuclease RRP42; Exosome component 7; FLJ26543; hRrp42p; KIAA0116; p8; Ribosomal RNA processing protein 42; Ribosomal RNA-processing protein 42; RRP42; Rrp42p.
Gene ID
23016
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Rat
Immunogen
21-120/291
Target
EXOSC7
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human EXOSC7
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
23016
Predicted Cross Reactivity
Mouse, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit
Curated Selection
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