Dermcidin Polyclonal Antibody, FITC Conjugated
Product Specifications
Background
Antimicrobial peptides participate in the innate response, which may provide a barrier for protection against infection. The Dermcidin gene encodes an antimicrobial peptide DCD-1, which is constitutively expressed in sweat glands, secreted into the sweat, and transported to the epidermal surface. DCD-1 displays antimicrobial activity in response to a variety of pathogenic microorganisms. Overexpression of Dermcidin in breast cancers promotes cell growth and survival, and is coupled with a focal copy number gain of its locus on human chromosome 12q13.2.
Synonyms
AIDD; DCD 1; dcd; DCD-1; DCD_HUMAN; DSEP; HCAP; P; Preproteolysin.
Gene ID
117159
Cellular Locus
Secreted
Host
Rabbit
Immunogen
63-109/110
Target
Dermcidin
Clonality
Polyclonal
Isotype
IgG
Conjugation
FITC
Source
KLH conjugated synthetic peptide derived from human Dermcidin/DCD
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
494nm/518nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
117159
Predicted Cross Reactivity
Human
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