Phospho-delta 1 Catenin (Tyr228) Polyclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity) . May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
Synonyms
Delta 1 Catenin phospho Y228; p-delta 1 Catenin phospho Y228; Cadherin associated Src substrate; Cadherin-associated Src substrate; CAS; Catenin cadherin associated protein delta 1; Catenin delta 1; Catenin delta-1; CTND1_HUMAN; CTNND 1; CTNND; CTNND1; KIAA0384; p120; P120 CAS; p120 catenin; P120 CTN; p120Cas; p120Ctn; P120CAS; P120CTN.
Gene ID
1500
Modification Site
Tyr228
Cellular Locus
Cytoplasm, Nucleus, Cell membrane
Host
Rabbit
Cross Reactivity
Mouse
Target
Phospho-delta 1 Catenin (Tyr228)
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic phosphopeptide derived from human delta 1 Catenin around the phosphorylation site of Tyr228
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1500
Predicted Cross Reactivity
Human, Rat
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