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DAPL1 Polyclonal Antibody, APC-Cy5.5 Conjugated

Product Specifications

Background

In contrast to growth factors which promote cell proliferation, FAS ligand (FAS-L) and the tumor necrosis factors (TNFs) rapidly induce apoptosis. Cellular response to FAS-L and TNF is mediated by structurally related receptors containing a conserved cytoplasmic region called the death domain?. DAPL1 (Death-associated protein-like 1), also known as EEDA (Early epithelial differentiation-associated protein), is a 107 amino acid protein that is expressed in hair follicles and is thought to function in a similar manner to DAP-1, possibly participating in the early stages of epithelial differentiation and/or apoptosis.

Synonyms

DapL1; DAPL1_HUMAN; death associated protein-like 1; Death-associated protein-like 1; Early epithelial dferentiation-associated protein; EEDA; RP23-151F21.4.

Gene ID

92196

Cellular Locus

Cytoplasm, Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

1-100/107

Target

DAPL1

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy5.5

Source

KLH conjugated synthetic peptide derived from human DAPL1

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/694nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

92196

Predicted Cross Reactivity

Mouse, Rat, Horse

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