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CSRP2 Polyclonal Antibody, Biotin Conjugated

Product Specifications

Background

CRP2 is a 193 amino acid nuclear protein that belongs to the CRP family of LIM domain proteins. Highly expressed in smooth muscle of aorta, CRP2 is thought to have a role in embryonic vascular system development and is downregulated following cell injury or PDGF-B exposure. CRP2 contains two LIM zinc-binding domains and is encoded by a gene that maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.

Synonyms

CRP 2; CRP2; CSRP2; CSRP2_HUMAN; Cysteine and glycine rich protein 2; Cysteine and glycine-rich protein 2; Cysteine rich protein 2; Cysteine-rich protein 2; LIM domain only 5 smooth muscle; LIM domain only protein 5; LMO 5; LMO-5; LMO5; SmLIM; Smooth muscle cell LIM protein.

Gene ID

1466

Cellular Locus

Nucleus

Host

Rabbit

Immunogen

101-193/193

Target

CSRP2

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human CSRP2

Applications

ELISA, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

1466

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Pig, Horse, Chicken, Rabbit

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