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CYP20A1 Polyclonal Antibody, FITC Conjugated

Product Specifications

Background

Cytochrome P450 proteins are heme-thiolate monooxygenases that mediate NADPH-dependent electron transport and function to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Specifically, Cytochrome P450s are responsible for metabolizing arachidonic acid to hydroxyeicosatetraenoic acid (a regulator of blood pressure) and epoxyeicosatrienoic acid (a molecule involved in signaling events) . CYP20A1 (cytochrome P450, family 20, subfamily A, polypeptide 1), also known as CYP-M, is a 462 amino acid single-pass membrane protein that belongs to the cytochrome P450 family. CYP20A1 is thought to carry its own oxygen as it lacks a conserved I-helix motif and one amino acid of its conserved heme binding site.

Synonyms

CP20A_HUMAN; CYP M; Cyp20a1; Cytochrome P450 20A1; Cytochrome P450 monooxygenase; Cytochrome P450, family 20, subfamily A, polypeptide 1; MGC22229.

Gene ID

57404

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

151-250/462

Target

CYP20A1

Clonality

Polyclonal

Isotype

IgG

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human CYP20A1

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

57404

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Pig, Guinea Pig, Zebrafish

Curated Selection

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