CYP20A1 Polyclonal Antibody, APC-Cy5.5 Conjugated
Product Specifications
Background
Cytochrome P450 proteins are heme-thiolate monooxygenases that mediate NADPH-dependent electron transport and function to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Specifically, Cytochrome P450s are responsible for metabolizing arachidonic acid to hydroxyeicosatetraenoic acid (a regulator of blood pressure) and epoxyeicosatrienoic acid (a molecule involved in signaling events) . CYP20A1 (cytochrome P450, family 20, subfamily A, polypeptide 1), also known as CYP-M, is a 462 amino acid single-pass membrane protein that belongs to the cytochrome P450 family. CYP20A1 is thought to carry its own oxygen as it lacks a conserved I-helix motif and one amino acid of its conserved heme binding site.
Synonyms
CP20A_HUMAN; CYP M; Cyp20a1; Cytochrome P450 20A1; Cytochrome P450 monooxygenase; Cytochrome P450, family 20, subfamily A, polypeptide 1; MGC22229.
Gene ID
57404
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Immunogen
151-250/462
Target
CYP20A1
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy5.5
Source
KLH conjugated synthetic peptide derived from human CYP20A1
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/694nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
57404
Predicted Cross Reactivity
Mouse, Rat, Dog, Cow, Pig, Guinea Pig, Zebrafish
Curated Selection
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