Phospho-CK18 (Ser52) Polyclonal Antibody, Cy5.5 Conjugated
Product Specifications
Background
When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity) . Together with KRT8, is involved in interleukin-6 (IL-6) -mediated barrier protection.
Synonyms
Keratin, type I cytoskeletal 18; Cytokeratin endo B; Keratin D; Cytokeratin-18; CK-18; Keratin-18; K18; Krt18; Kerd; Krt1-18
Gene ID
16668
Modification Site
Ser52
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Mouse, Rat
Target
Phospho-CK18 (Ser52)
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy5.5
Source
KLH conjugated synthetic phosphopeptide derived from mouse CK18 around the phosphorylation site of Ser52 [SR (p-S) VW]
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
675nm/694nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
16668
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