ASPP2 Polyclonal Antibody, Biotin Conjugated

Product Specifications

Background

Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

Synonyms

BBP; 53BP2; ASPP2; P53BP2; PPP1R13A; Apoptosis-stimulating of p53 protein 2; Bcl2-binding protein; Renal carcinoma antigen NY-REN-51; Tumor suppressor p53-binding protein 2; p53-binding protein 2; TP53BP2

Gene ID

7159

Swiss Prot

Q13625

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse

Immunogen

1001-1128/1128

Target

ASPP2

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human ASPP2

Applications

WB, ELISA, IHC-P

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

7159

Predicted Cross Reactivity

Chicken

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

TA506000S 30 µL

Parvin alpha (PARVA) Mouse Monoclonal Antibody [Clone ID: OTI2B11]

Ask

View Details

MBS1027279-01 0.02 mg (E-Coli)

Recombinant Escherichia coli O127:H6 DNA replication terminus site-binding protein (tus)

Ask

View Details

MBS1027279-02 0.02 mg (Yeast)

Recombinant Escherichia coli O127:H6 DNA replication terminus site-binding protein (tus)

Ask

View Details

MBS1027279-03 0.1 mg (E-Coli)

Recombinant Escherichia coli O127:H6 DNA replication terminus site-binding protein (tus)

Ask

View Details

MBS1027279-04 0.1 mg (Yeast)

Recombinant Escherichia coli O127:H6 DNA replication terminus site-binding protein (tus)

Ask

View Details

MBS1027279-05 0.02 mg (Baculovirus)

Recombinant Escherichia coli O127:H6 DNA replication terminus site-binding protein (tus)

Ask

View Details