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VAC14 Polyclonal Antibody, PerCP Conjugated

Product Specifications

Background

The content of phosphatidylinositol 3,5-bisphosphate (PtdIns (3,5) P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns (3,5) P2. Other components of this complex are the PtdIns (3,5) P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns (3,5) P2 phosphatase FIG4 (MIM 609390) . VAC14 functions as an activator of PIKFYVE (Sbrissa et al., 2007 [PubMed 17556371]) .[supplied by OMIM, Feb 2010]

Synonyms

ArPIKfyve; FLJ10305; FLJ36622; FLJ46582; MGC149815; MGC149816; OTTHUMP00000174908; Protein VAC14 homolog; Tax1 (human T cell leukemia virus type I) binding protein 1; Tax1 (human T cell leukemia virus type I) binding protein 2; Tax1 binding protein 2; Tax1-binding protein 2; TAX1BP2; TRX; VAC 14; vac14; Vac14 homolog (S. cerevisiae) ; Vac14 homolog; VAC14_HUMAN.

Gene ID

55697

Swiss Prot

Q08AM6

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

1-50/782

Target

VAC14

Clonality

Polyclonal

Isotype

IgG

Conjugation

PerCP

Source

KLH conjugated synthetic peptide derived from human VAC14

Applications

IF (ICC), IF

Purification

Purified by Protein A.

Excitation Emission

482nm/677nm

Concentration

1µg/µl

Dilution

IF (ICC) (1:50-200), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

55697

Predicted Cross Reactivity

Human, Rat, Dog, Cow, Pig, Horse, Chicken, Rabbit, Zebrafish

Curated Selection

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