VAC14 Polyclonal Antibody, APC-Cy7 Conjugated

The content of phosphatidylinositol 3,5-bisphosphate (PtdIns (3,5) P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns (3,5) P2. Other components of this complex are the PtdIns (3,5) P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns (3,5) P2 phosphatase FIG4 (MIM 609390) . VAC14 functions as an activator of PIKFYVE (Sbrissa et al., 2007 [PubMed 17556371]) .[supplied by OMIM, Feb 2010]

ArPIKfyve; FLJ10305; FLJ36622; FLJ46582; MGC149815; MGC149816; OTTHUMP00000174908; Protein VAC14 homolog; Tax1 (human T cell leukemia virus type I) binding protein 1; Tax1 (human T cell leukemia virus type I) binding protein 2; Tax1 binding protein 2; Tax1-binding protein 2; TAX1BP2; TRX; VAC 14; vac14; Vac14 homolog (S. cerevisiae) ; Vac14 homolog; VAC14_HUMAN.