Phospho-PDGFRA (Tyr720) Polyclonal Antibody, AbBy Fluor™ 405 Conjugated
Product Specifications
Background
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]
Synonyms
PDGF Receptor alpha (phospho Y720) ; p-PDGF Receptor alpha (phospho Y720) ; Alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a; CD140a antigen; MGC74795; PDGF alpha chain; PDGF-R-alpha; PDGFR 2; PDGFR alpha; PDGFR2; PDGFRA; PDGFRA/BCR fusion; PGFRA_HUMAN; Platelet derived growth factor receptor 2; Platelet derived growth factor receptor alpha; Platelet derived growth factor receptor alpha polypeptide; Platelet derived growth factor receptor; Rearranged in hypereosinophilia platelet derived growth factor receptor alpha fusion protein; RHEPDGFRA.
Gene ID
5156
Swiss Prot
P16234
Modification Site
Tyr720
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
Phospho-PDGFRA (Tyr720)
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 405
Source
KLH conjugated synthesised phosphopeptide derived from human PDGFRA around the phosphorylation site of Tyr720
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
401nm/421nm
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.biossantibodies.com/datasheets/bs-12595R-BF405
Gene ID URL
5156
Predicted Cross Reactivity
Mouse, Rat, Cow, Sheep, Pig, Horse, Chicken, Rabbit
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items