Monophosphoryl lipid A
Monophosphoryl lipid A (Glucopyranosyl lipid A) is a toll-like receptor 4 agonist. Monophosphoryl lipid A is derived from the cell wall of nonpathogenic Salmonella. Monophosphoryl lipid A can be used for the research of immunization and vaccine[1].
Product Specifications
CAS Number
1246298-63-4
Product Name Alternative
Glucopyranosyl lipid A
UNSPSC
12352005
Hazard Statement
H335, H371, H373
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/monophosphoryl-lipid-a.html
Purity
99.31
Smiles
CCCCCCCCCCCCCC(O[C@@H](CC(N[C@@H]1[C@@H](OC(C[C@H](OC(CCCCCCCCCCCCC)=O)CCCCCCCCCCC)=O)[C@H](OP(O)([O-])=O)[C@@H](CO)O[C@H]1OC[C@@H]2[C@@H](O)[C@H](OC(C[C@H](O)CCCCCCCCCCC)=O)[C@@H](NC(C[C@H](O)CCCCCCCCCCC)=O)[C@@H](O)O2)=O)CCCCCCCCCCC)=O.[NH4+]
Molecular Formula
C96H184N3O22P
Molecular Weight
1763.47
Precautions
H335, H371, H373
References & Citations
[1]Cheng R, et al. Recombination Monophosphoryl Lipid A-Derived Vacosome for the Development of Preventive Cancer Vaccines. ACS Appl Mater Interfaces. 2020;12 (40) :44554-44562.|[2]Ismaili J, et al. Monophosphoryl lipid A activates both human dendritic cells and T cells. J Immunol. 2002;168 (2) :926-932.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
TLR4
Available Sizes
Frequently Asked Questions
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