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FGF4 Polyclonal Antibody, APC Conjugated

Product Specifications

Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. [provided by RefSeq].

Synonyms

Fibroblast Growth Factor4; Heparin Secretory Transforming Protein 1; Kaposi Sarcoma Oncogene; Fgf-4; Fgfk; Hstf-1; kFGF; KS3; MGC129266; MGC129267; HBGF-4; HST; HST-1; HSTF1; K-FGF; KS3; FGF4_HUMAN.

Gene ID

2249

Cellular Locus

Secreted

Host

Rabbit

Immunogen

101-206/206

Target

FGF4

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human FGF4

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2249

Predicted Cross Reactivity

Human, Mouse, Rat

Curated Selection

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