Apolipoprotein CII/APOC2 Polyclonal Antibody, PE-Cy7 Conjugated

Apolipoproteins are protein components of plasma lipoproteins (1) . The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which specifically modulate the metabolism of triglyceride-rich lipoproteins (2) . The human apoC-I gene maps to chromosome 19q13.2 and is expressed primarily in the liver where it is activated when monocytes differentiate into macrophages (3,4) . The human apoC-II gene maps to chromosome 19q13.2 and encodes a 79 amino acid single chain protein that is a necessary cofactor for the activation of lipoprotein lipase, the enzyme that hydrolyzes triglycerides in plasma and transfers the fatty acids to tissues (57) . The human apoC-III gene maps to chromosome 11q23 and encodes a protein that may delay catabolism of triglyceride-rich particles by inhibiting lipoprotein lipase and hepatic lipase (8) . The human apoC-IV gene maps to chromosome 19q13.2 and encodes a 127 amino acid protein that is primarily expressed in the liver (9,10) .

APC 2; APC2; Apo CII; APOC 2; ApoC II; apoC-II ; APOC2; APOC2 protein; ApoCII; Apolipoprotein C II; Apolipoprotein C II precursor; ApolipoproteinCII; MGC75082